T cell immunity ameliorates COVID-19 disease severity and provides post-exposure prophylaxis after peptide-vaccination, in Syrian hamsters

T cell immunity ameliorates COVID-19 disease severity and provides post-exposure prophylaxis after peptide-vaccination, in Syrian hamsters

BackgroundThe emergence of novel SARS-CoV-2 variants that resist neutralizing antibodies drew the attention to cellular immunity and calls for the development of alternative vaccination strategies to combat the pandemic. Here, we have assessed the kinetics of T cell responses and protective efficacy...

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Bibliographic Details
Main Authors: Eszter Somogyi, Mariann Kremlitzka, Zsolt Csiszovszki, Levente Molnár, Orsolya Lőrincz, József Tóth, Leon de Waal, Sofie Pattijn, Wencke Reineking, Andreas Beineke, Enikő R. Tőke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
T cells
post-exposure prophylaxis
therapeutic
vaccine
SARS-CoV-2
adaptive immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111629/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111629/full

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