Redox regulation of DUBs and its therapeutic implications in cancer
Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. An imbalance between ROS generation and the antioxi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-12-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231721003542 |