Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products

Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products

Patients receiving anti-retroviral drug treatment are sometimes simultaneously taking herbal remedies, which may result in pharmacokinetic herb-drug interactions. This study aimed to determine if pharmacokinetic interactions exist between selected commercially available herbal products (i.e., Lincta...

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Bibliographic Details
Main Authors: Carlemi Calitz, Chrisna Gouws, Joe Viljoen, Jan Steenekamp, Lubbe Wiesner, Efrem Abay, Josias Hamman
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
herb-drug interactions
efflux
P-glycoprotein
cytochrome P450
Caco-2
LS180
metabolism
Online Access:http://www.mdpi.com/1420-3049/20/12/19838

Internet

http://www.mdpi.com/1420-3049/20/12/19838

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