Characteristics of sodium and water retention in rats with nephrotic syndrome induced by puromycin aminonucleoside

Abstract Introduction Nephrotic syndrome (NS) is characterized by renal sodium and water retention. The mechanisms are not fully elucidated. Methods The NS rat model was established by single intraperitoneal injection of 100 mg/kg puromycin aminonucleoside (PAN). The plasma electrolyte level and uri...

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Bibliographic Details
Main Authors: Zaiping Xu, Yunlai Wang, Ye Feng, Mo Yang, Gaoxiang Shi, Zihua Xuan, Fan Xu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-023-03367-z