Dysregulated CD25 and Cytokine Expression by γδ T Cells of Systemic Sclerosis Patients Stimulated With Cardiolipin and Zoledronate

Dysregulated CD25 and Cytokine Expression by γδ T Cells of Systemic Sclerosis Patients Stimulated With Cardiolipin and Zoledronate

Objectivesγδ T cells, a non-conventional innate lymphocyte subset containing cells that can be activated by lipids and phosphoantigens, are abnormally regulated in systemic sclerosis (SSc). To further evaluate the significance of this dysregulation, we compared how exposure to an autoantigenic lipid...

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Bibliographic Details
Main Authors: Helena Migalovich Sheikhet, Jose Villacorta Hidalgo, Paul Fisch, Alexandra Balbir-Gurman, Yolanda Braun-Moscovici, Ilan Bank
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
cardiolipin
systemic sclerosis
fibrosis
γδ T cells
zoledronate
phosphoantigens
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00753/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00753/full

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