The Modulation of Cholesterol Metabolism Is Involved in the Antiviral Effect of Nitazoxanide

The Modulation of Cholesterol Metabolism Is Involved in the Antiviral Effect of Nitazoxanide

We previously investigated the role of Nitazoxanide (NTZ), a thiazolide endowed with antiviral and antiparasitic activity, in HIV-1 infection. NTZ treatment in primary isolated PBMCs was able to reduce HIV-1 infection in vitro by inducing the expression of a number of type-I interferon-stimulated ge...

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Bibliographic Details
Main Authors: Claudio Fenizia, Salomè Valentina Ibba, Claudia Vanetti, Sergio Strizzi, Jean-François Rossignol, Mara Biasin, Daria Trabattoni, Mario Clerici
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Infectious Disease Reports
Subjects:
nitazoxanide
thiazolide
cholesterol metabolism
antiviral
FLU
interferon
Online Access:https://www.mdpi.com/2036-7449/13/3/60

Internet

https://www.mdpi.com/2036-7449/13/3/60

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