Herpes simplex virus type 2 triggers reactivation of Kaposi's sarcoma-associated herpesvirus from latency and collaborates with HIV-1 Tat.

Kaposi's sarcoma-associated herpesvirus (KSHV) infection was necessary but not sufficient for Kaposi's sarcoma (KS) development without other cofactors. Previously, we identified that both human immunodeficiency type 1 (HIV-1) Tat and herpes simplex virus 1 (HSV-1) were important cofactors...

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Bibliographic Details
Main Authors: Qiao Tang, Di Qin, Zhigang Lv, Xiaolei Zhu, Xinting Ma, Qin Yan, Yi Zeng, Yuanyuan Guo, Ninghan Feng, Chun Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3276581?pdf=render