Acceleration of enzymatic catalysis by active hydrodynamic fluctuations

Cells are teeming with biochemical nano-machines whose vigorous activity generates strong hydrodynamic fluctuations. The authors revamp transition-state theory to account for the effect of this active noise and find that it may significantly accelerate the turnover rate of enzymes, thus proposing a...

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Bibliographic Details
Main Authors: Ashwani Kr. Tripathi, Tamoghna Das, Govind Paneru, Hyuk Kyu Pak, Tsvi Tlusty
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Communications Physics
Online Access:https://doi.org/10.1038/s42005-022-00878-3