The organization of classical satellite DNAs in human chromosomes: an approach using AluI and TaqI restriction endonucleases

Human classical satellite DNAs were used as probes to investigate the molecular mechanism(s) of AluI/TaqI attack in situ on specific centromeric areas. The biochemical results obtained show that the majority of such highly repetitive DNAs are not solubilized from chromosomes, in spite of a cleavage...

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Bibliographic Details
Main Authors: M Nieddu, G Pichiri, G Diaz, R Mezzanotte
Format: Article
Language:English
Published: PAGEPress Publications 2009-06-01
Series:European Journal of Histochemistry
Online Access:https://www.ejh.it/index.php/ejh/article/view/829