Prolonging somatic cell proliferation through constitutive hox gene expression in C. elegans

Abstract hox genes encode a conserved family of homeodomain transcription factors that are essential to determine the identity of body segments during embryogenesis and maintain adult somatic stem cells competent to regenerate organs. In contrast to higher organisms, somatic cells in C. elegans irre...

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Bibliographic Details
Main Authors: Svenia D. Heinze, Simon Berger, Stefanie Engleitner, Michael Daube, Alex Hajnal
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42644-1