A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment

A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment

Background: Nonalcoholic steatohepatitis (NASH) has caused a significant burden on public health care systems, the economy and society. However, there has still been no officially approved pharmacotherapy for NASH. It has been suggested that oxidative stress and mitochondrial dysfunction play vital...

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Bibliographic Details
Main Authors: Mingtai Chen, Furong Huang, Bohao Chen, Junli Kang, Yijing Yao, Mengnan Liua, Yuanyuan Li, Yaqin Li, Tianran Zhou, Deti Peng, Lidan Luo, Chunshan Wei, Yufeng Xing, Qibiao Wu, Hua Zhou, Guangdong Tong
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Herbal medicine
Nonalcoholic steatohepatitis
Mitochondria
Bioinformatics analysis
UPLC-HRMS
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016293

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http://www.sciencedirect.com/science/article/pii/S0753332223016293

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