The Vault Complex Is Significantly Involved in Therapeutic Responsiveness of Endocrine Tumors and Linked to Autophagy under Chemotherapeutic Conditions

The Vault Complex Is Significantly Involved in Therapeutic Responsiveness of Endocrine Tumors and Linked to Autophagy under Chemotherapeutic Conditions

Cancers display dynamic interactions with their complex microenvironments that influence tumor growth, invasiveness, and immune evasion, thereby also influencing potential resistance to therapeutic treatments. The tumor microenvironment (TME) includes cells of the immune system, the extracellular ma...

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Bibliographic Details
Main Authors: Stefan Bornstein, Igor Shapiro, Alekhya Mazumdar, Kathrin Zitzmann, Svenja Nölting, Edlira Luca, Felix Beuschlein, Ashish Sharma, Constanze Hantel
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
autophagy
vault RNA
vault complex
MVP
VPARP
TEP-1
Online Access:https://www.mdpi.com/2072-6694/15/6/1783

Internet

https://www.mdpi.com/2072-6694/15/6/1783

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