In Silico Approaches to Developing Novel Glycogen Synthase Kinase 3β (GSK-3β)

In Silico Approaches to Developing Novel Glycogen Synthase Kinase 3β (GSK-3β)

Alzheimer’s disease (AD) is caused by plaque agglomeration and entanglement in several areas of the neural cells, which leads to apoptosis. The main etiology of AD is senile dementia, which is linked to amyloid-beta (Aβ) deregulation and tau perivascular pathogeny. Hyperphosphorylated tau has a prop...

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Bibliographic Details
Main Authors: Shuchi Goyal, Manjinder Singh, Divya Thirumal, Pratibha Sharma, Somdutt Mujwar, Krishna Kumar Mishra, Thakur Gurjeet Singh, Ravinder Singh, Varinder Singh, Tanveer Singh, Sheikh F. Ahmad
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
GSK-3β
molecular dynamics
docking
scaffold
morphing
neurofibrillary tangles
Online Access:https://www.mdpi.com/2227-9059/11/10/2784

Internet

https://www.mdpi.com/2227-9059/11/10/2784

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