Roles of host proteases in the entry of SARS-CoV-2

Abstract The spike protein (S) of SARS-CoV-2 is responsible for viral attachment and entry, thus a major factor for host susceptibility, tissue tropism, virulence and pathogenicity. The S is divided with S1 and S2 region, and the S1 contains the receptor-binding domain (RBD), while the S2 contains t...

Full description

Bibliographic Details
Main Authors: Alexandria Zabiegala, Yunjeong Kim, Kyeong-Ok Chang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Animal Diseases
Online Access:https://doi.org/10.1186/s44149-023-00075-x