Prion protein gene mutation detection using long-read Nanopore sequencing

Prion protein gene mutation detection using long-read Nanopore sequencing

Abstract Prion diseases are fatal neurodegenerative conditions that affect humans and animals. Rapid and accurate sequencing of the prion gene PRNP is paramount to human prion disease diagnosis and for animal surveillance programmes. Current methods for PRNP genotyping involve sequencing of small fr...

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Bibliographic Details
Main Authors: François Kroll, Athanasios Dimitriadis, Tracy Campbell, Lee Darwent, John Collinge, Simon Mead, Emmanuelle Vire
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12130-7

Internet

https://doi.org/10.1038/s41598-022-12130-7

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