Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis

Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis

The innate immune system is rapidly activated during myocardial infarction and blockade of extracellular complement system reduces infarct size. Intracellular complement, however, appears to be closely linked to metabolic pathways and its role in ischemia-reperfusion injury is unknown and may be dif...

Full description

Bibliographic Details
Main Authors: M-K. Torp, T. Ranheim, C. Schjalm, M. Hjorth, C.M. Heiestad, K. T. Dalen, P. H. Nilsson, T. E. Mollnes, S. E. Pischke, E. Lien, J. Vaage, A. Yndestad, K-O. Stensløkken
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
ischemia-reperfusion injury
complement system
intracellular C3
metabolism
cardiology (basic/technical)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.870811/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.870811/full

Similar Items