Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus

Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus

Dengue virus (DENV) infection continues to be a public health challenge, lacking a specific cure. Vaccination remains the primary strategy against dengue; however, existing live-attenuated vaccines display variable efficacy across four serotypes, influenced by host serostatus and age, and predominan...

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Bibliographic Details
Main Authors: Nilanshu Manocha, Daphné Laubreton, Xavier Robert, Jacqueline Marvel, Virginie Gueguen-Chaignon, Patrice Gouet, Prashant Kumar, Madhu Khanna
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Vaccines
Subjects:
dengue virus
immunization
cross-serotype protection
cellular immunity
multiepitope vaccine
MHC I-binding epitopes
Online Access:https://www.mdpi.com/2076-393X/12/3/316

Internet

https://www.mdpi.com/2076-393X/12/3/316

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