Formyl-Peptide Receptor 2 Signaling Modulates SLC7A11/xCT Expression and Activity in Tumor Cells

Formyl-Peptide Receptor 2 Signaling Modulates SLC7A11/xCT Expression and Activity in Tumor Cells

Cancer cells exhibit high levels of oxidative stress and consequently require a high amount of cysteine for glutathione synthesis. Solute Carrier Family 7 Member 11 (SLC7A11), or xCT, mediates the cellular uptake of cystine in exchange for intracellular glutamate; imported extracellular cystine is r...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Tiziana Pecchillo Cimmino, Carolina Punziano, Iolanda Panico, Zeudi Petrone, Myrhiam Cassese, Raffaella Faraonio, Vincenza Barresi, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2024-04-01
Ráidu:Antioxidants
Fáttát:
formyl-peptide receptor 2
NADPH oxidase
SLC7A11/xCT
glutathione
lipid peroxidation
NRF2
Liŋkkat:https://www.mdpi.com/2076-3921/13/5/552

Interneahtta

https://www.mdpi.com/2076-3921/13/5/552

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