IL-10 Mediated Immunomodulation Limits Subepithelial Fibrosis and Repairs Airway Epithelium in Rejecting Airway Allografts

IL-10 Mediated Immunomodulation Limits Subepithelial Fibrosis and Repairs Airway Epithelium in Rejecting Airway Allografts

Interleukin-10 plays a vital role in maintaining peripheral immunotolerance and favors a regulatory immune milieu through the suppression of T effector cells. Inflammation-induced microvascular loss has been associated with airway epithelial injury, which is a key pathological source of graft malfun...

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Bibliographic Details
Main Authors: Mohammad Afzal Khan, Ghazi Abdulmalik Ashoor, Talal Shamma, Fatimah Alanazi, Abdullah Altuhami, Shadab Kazmi, Hala Abdalrahman Ahmed, Abdullah Mohammed Assiri, Dieter Clemens Broering
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
interleukin-10
immunotolerance
subepithelial fibrosis
TSG-6
Online Access:https://www.mdpi.com/2073-4409/10/5/1248

Internet

https://www.mdpi.com/2073-4409/10/5/1248

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