Evidence and Potential Mechanism of Action of Lithospermum erythrorhizon and Its Active Components for Psoriasis

Background: Traditional Chinese medicine is effective in the treatment of psoriasis and can significantly reduce skin inflammation and psoriatic lesions with minimal side effects. Shikonin (SHI) and β,β-dimethylacryloyl alkannin (DMA), the main active components of Lithospermum erythrorhizon, have s...

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Main Authors: Jiao Wang, Liu Liu, Xiao-Ying Sun, Shuo Zhang, Ya-Qiong Zhou, Kan Ze, Si-Ting Chen, Yi Lu, Xiao-Ce Cai, Jia-Le Chen, Ying Luo, Yi Ru, Bin Li, Xin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.781850/full