NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy

NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy

Non-small cell lung cancer (NSCLC) is largely promoted by a multistep tumorigenesis process involving various genetic and epigenetic alterations, which essentially contribute to the high incidence of mortality among patients with NSCLC. Clinical observations revealed that NSCLC also co-opts a multif...

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Bibliographic Details
Main Authors: Leona Raskova Kafkova, Joanna M. Mierzwicka, Prosenjit Chakraborty, Petr Jakubec, Ondrej Fischer, Jozef Skarda, Petr Maly, Milan Raska
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
PD-1
PD-L1
immune checkpoint
NSCLC
CTLA-4
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1342086/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1342086/full

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