N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression

N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression

Background/purpose: Mechanical stress plays a vital role in osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Cyclic mechanical stress may up-regulate reactive oxygen species (ROS) level. N-acetylcysteine (NAC) possesses powerful antioxidant capacity. However, it is undefined t...

Full description

Bibliographic Details
Main Authors: Xun Xi, Zi-Xuan Li, Yi Zhao, Hong Liu, Shuai Chen, Dong-Xu Liu
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Dental Sciences
Subjects:
Mechanical stress
N-acetylcysteine
Orthodontic tooth movement
Periodontal ligament
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S199179022100249X

Internet

http://www.sciencedirect.com/science/article/pii/S199179022100249X

Similar Items