Piperlongumine alleviates corneal allograft rejection via suppressing angiogenesis and inflammation

BackgroundNeovascularization and inflammatory response are two essential features of corneal allograft rejection. Here, we investigated the impact of Piperlongumine (PL) on alleviating corneal allograft rejection, primarily focusing on pathological angiogenesis and inflammation.MethodsA murine corne...

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Bibliographic Details
Main Authors: Xiangyu Fan, Jini Qiu, Tianjie Yuan, Jing Zhang, Jianjiang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1090877/full