Development and validation of a multiplex real-time qPCR assay using GMP-grade reagents for leprosy diagnosis.

Development and validation of a multiplex real-time qPCR assay using GMP-grade reagents for leprosy diagnosis.

Leprosy is a chronic dermato-neurological disease caused by Mycobacterium leprae, an obligate intracellular bacterium. Timely detection is a challenge in leprosy diagnosis, relying on clinical examination and trained health professionals. Furthermore, adequate care and transmission control depend on...

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Bibliographic Details
Main Authors: Fernanda Saloum de Neves Manta, Thiago Jacomasso, Rita de Cássia Pontello Rampazzo, Suelen Justo Maria Moreira, Najua M Zahra, Stewart T Cole, Charlotte Avanzi, Thyago Leal-Calvo, Sidra Ezidio Gonçalves Vasconcellos, Phillip Suffys, Marcelo Ribeiro-Alves, Marco Aurelio Krieger, Alexandre Dias Tavares Costa, Milton Ozório Moraes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009850

Internet

https://doi.org/10.1371/journal.pntd.0009850

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