Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity

Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity

Abstract Peroxiredoxin 6 (PRDX6) is expressed dominantly in the astrocytes and exerts either neuroprotective or neurotoxic effects in the brain. Although PRDX6 can modulate several signaling cascades involving cognitive functions, its physiological role in spatial memory has not been investigated ye...

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Bibliographic Details
Main Authors: Sarayut Phasuk, Sureka Jasmin, Tanita Pairojana, Hsueh-Kai Chang, Kai-Chi Liang, Ingrid Y. Liu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Molecular Brain
Subjects:
Peroxiredoxin 6
Spatial memory
Long-term potentiation
Neuroinflammation
Reactive astrocyte
Online Access:https://doi.org/10.1186/s13041-021-00779-6

Internet

https://doi.org/10.1186/s13041-021-00779-6

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