Highly efficient concentration of lenti- and retroviral vector preparations by membrane adsorbers and ultrafiltration

<p>Abstract</p> <p>Background</p> <p>Lentiviral vectors (LVs) can efficiently transduce a broad spectrum of cells and tissues, including dividing and non-dividing cells. So far the most widely used method for concentration of lentiviral particles is ultracentrifugation...

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Bibliographic Details
Main Authors: Muelich Jutta, Kocourek Andreas, Scheibe Oliver, Zimmermann Katrin, Jurkiewicz Elke, Pfeifer Alexander
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/55