DRD2/CHRNA5 interaction on prefrontal biology and physiology during working memory.

Prefrontal behavior and activity in humans are heritable. Studies in animals demonstrate an interaction between dopamine D2 receptors and nicotinic acetylcholine receptors on prefrontal behavior but evidence in humans is weak. Therefore, we hypothesize that genetic variation regulating dopamine D2 a...

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Main Authors: Annabella Di Giorgio, Ryan M Smith, Leonardo Fazio, Enrico D'Ambrosio, Barbara Gelao, Aldo Tomasicchio, Pierluigi Selvaggi, Paolo Taurisano, Tiziana Quarto, Rita Masellis, Antonio Rampino, Grazia Caforio, Teresa Popolizio, Giuseppe Blasi, Wolfgang Sadee, Alessandro Bertolino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018353?pdf=render