Characterisation of unessential genes required for survival under conditions of DNA stress
Abstract Background Genomic instability is a hallmark of cancer. Cancer progression depends on the development and amplification of mutations that alter the cellular response to threats to the genome. This can lead to DNA replication stress and the potential loss of genetic integrity of the newly fo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
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Series: | Journal of Genetic Engineering and Biotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s43141-020-00025-x |