Characterisation of unessential genes required for survival under conditions of DNA stress

Abstract Background Genomic instability is a hallmark of cancer. Cancer progression depends on the development and amplification of mutations that alter the cellular response to threats to the genome. This can lead to DNA replication stress and the potential loss of genetic integrity of the newly fo...

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Bibliographic Details
Main Authors: Hassan Ahmed Ezzat, Clive Price
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s43141-020-00025-x