Characterisation of unessential genes required for survival under conditions of DNA stress
Abstract Background Genomic instability is a hallmark of cancer. Cancer progression depends on the development and amplification of mutations that alter the cellular response to threats to the genome. This can lead to DNA replication stress and the potential loss of genetic integrity of the newly fo...
Main Authors: | Hassan Ahmed Ezzat, Clive Price |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
|
Series: | Journal of Genetic Engineering and Biotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s43141-020-00025-x |
Similar Items
-
The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning
by: Chiaki Noguchi, et al.
Published: (2019-04-01) -
BLM Sumoylation Is Required for Replication Stability and Normal Fork Velocity During DNA Replication
by: Christelle de Renty, et al.
Published: (2022-07-01) -
<i>DNA2</i> in Chromosome Stability and Cell Survival—Is It All about Replication Forks?
by: Jessica J. R. Hudson, et al.
Published: (2021-04-01) -
Recent advances in the genome-wide study of DNA replication origins in yeast
by: Chong ePeng, et al.
Published: (2015-02-01) -
DNA Damage Response Pathway and Replication Fork Stress During Oligonucleotide Directed Gene Editing
by: Melissa Bonner, et al.
Published: (2012-01-01)