Gene expression of desaturase (FADS1 and FADS2) and Elongase (ELOVL5) enzymes in peripheral blood: association with polyunsaturated fatty acid levels and atopic eczema in 4-year-old children.

BACKGROUND:It is unknown if changes in the gene expression of the desaturase and elongase enzymes are associated with abnormal n-6 long chain polyunsaturated fatty acid (LC-PUFA) levels in children with atopic eczema (AE). We analyzed whether mRNA-expression of genes encoding key enzymes of LC-PUFA...

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Main Authors: Aida Maribel Chisaguano, Rosa Montes, Teresa Pérez-Berezo, Ana Isabel Castellote, Marcela Guerendiain, Mariona Bustamante, Eva Morales, Raquel García-Esteban, Jordi Sunyer, Angels Franch, M Carmen López-Sabater
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805510?pdf=render