A Novel Feedback Loop That Controls Bimodal Expression of Genetic Competence.
Gene expression can be highly heterogeneous in isogenic cell populations. An extreme type of heterogeneity is the so-called bistable or bimodal expression, whereby a cell can differentiate into two alternative expression states. Stochastic fluctuations of protein levels, also referred to as noise, p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4482431?pdf=render |