CD4+CD25+ T regulatory cells in renal transplantation

CD4+CD25+ T regulatory cells in renal transplantation

The immune response to an allograft activates lymphocytes with the capacity to cause rejection. Activation of CD4+CD25+Foxp3+T regulatory cells (Treg) can down-regulate allograft rejection and can induce immune tolerance to the allograft. Treg represent <10% of peripheral CD4+T cells and do n...

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Bibliographic Details
Main Authors: Jason Cheung, Beata Zahorowska, Michael Suranyi, Jeffrey K. W. Wong, Jason Diep, Stephen T. Spicer, Nirupama D. Verma, Suzanne J. Hodgkinson, Bruce M. Hall
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
regulatory T cell
transplant tolerance
Treg
transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1017683/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1017683/full

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