iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

Skeletal muscle myoblasts (iMyoblasts) were generated from human induced pluripotent stem cells (iPSCs) using an efficient and reliable transgene-free induction and stem cell selection protocol. Immunofluorescence, flow cytometry, qPCR, digital RNA expression profiling, and scRNA-Seq studies identif...

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Bibliographic Details
Main Authors: Dongsheng Guo, Katelyn Daman, Jennifer JC Chen, Meng-Jiao Shi, Jing Yan, Zdenka Matijasevic, Amanda M Rickard, Monica H Bennett, Alex Kiselyov, Haowen Zhou, Anne G Bang, Kathryn R Wagner, René Maehr, Oliver D King, Lawrence J Hayward, Charles P Emerson Jr
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
human ipsc myogenesis
muscle stem cells
iMyoblasts
xenograft
Online Access:https://elifesciences.org/articles/70341

Internet

https://elifesciences.org/articles/70341

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