PIMT prevents the apoptosis of endothelial cells in response to glycated low density lipoproteins and protective effects of grape seed procyanidin B2.

The development of diabetic angiopathy is associated with profound vascular endothelial cells (VEC) dysfunction and apoptosis. Glycated low density lipoproteins (gly-LDL) continuously produced in the setting of diabetic patients play an important role in causing VEC dysfunction and apoptosis. Howeve...

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Bibliographic Details
Main Authors: Xiao-li Li, Bao-ying Li, Mei Cheng, Fei Yu, Wen-bin Yin, Qian Cai, Zhen Zhang, Jian-hua Zhang, Jun-fu Wang, Rui-hai Zhou, Hai-qing Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724603?pdf=render