Negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cells and patient prognosis after breast cancer surgery

Abstract Objective To investigate how the negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cell lines and prognosis in postoperative breast cancer patients. Methods RT-PCR, qRT-PCR, and western blot assays were used to detect the expression of CD44s, CD44v6,...

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Bibliographic Details
Main Authors: Fang Xin Jian, Peng Xiao Bao, Wang Fu Li, Yan Hai Cui, Hang Guan Hong
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-10738-0