Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes

Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes

Abstract Tumour‐draining lymph nodes (LNs) undergo massive remodelling including expansion of the lymphatic sinuses, a process that has been linked to lymphatic metastasis by creation of a pre‐metastatic niche. However, the signals leading to these changes have not been completely understood. Here,...

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Bibliographic Details
Main Authors: Noelle Leary, Sarina Walser, Yuliang He, Nikola Cousin, Paulo Pereira, Alessandro Gallo, Victor Collado‐Diaz, Cornelia Halin, Susana Garcia‐Silva, Hector Peinado, Lothar C. Dieterich
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Journal of Extracellular Vesicles
Subjects:
exosome
immunotherapy
lymphangiogenesis
pre‐metastatic niche
sentinel lymph node
Online Access:https://doi.org/10.1002/jev2.12197

Internet

https://doi.org/10.1002/jev2.12197

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