Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase

Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase

Synthetic strategies for optically controlling gene expression may enable the precise spatiotemporal control of genes in any combination of cells that cannot be targeted with specific promoters. We develop an improved genetic code expansion system in Caenorhabditis elegans and use it to create a pho...

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Bibliographic Details
Main Authors: Lloyd Davis, Inja Radman, Angeliki Goutou, Ailish Tynan, Kieran Baxter, Zhiyan Xi, Jack M O'Shea, Jason W Chin, Sebastian Greiss
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
genetic code expansion
non canonical amino acids
optogenetics
Cre recombinase
photo-caged amino acid
Online Access:https://elifesciences.org/articles/67075

Internet

https://elifesciences.org/articles/67075

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