Renin–angiotensin–aldosterone system blockers and region-specific variations in COVID-19 outcomes: findings from a systematic review and meta-analysis

Background and aims:  Coronavirus disease 2019 (COVID-19) has been observed to cause a high mortality in people with cardiometabolic diseases. Renin–angiotensin–aldosterone system (RAAS) blockers enhance the expression of ACE2, the binding receptor of SARS-CoV-2, and can enhance viral infectivity. W...

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Bibliographic Details
Main Authors: Upinder Kaur, Sankha Shubhra Chakrabarti, Tejas K. Patel
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:Therapeutic Advances in Drug Safety
Online Access:https://doi.org/10.1177/20420986211011345