Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression

Abstract Exosomes are involved in a wide range of biological processes in human cells. Considerable evidence suggests that engineered exosomes (eExosomes) containing therapeutic agents can attenuate the oncogenic activity of human cancer cells. Despite its biomedical relevance, no information has be...

Full description

Bibliographic Details
Main Authors: Yutaro Kase, Katsuhiro Uzawa, Sho Wagai, Shusaku Yoshimura, Jun-Ichiro Yamamoto, Yuriko Toeda, Megumi Okubo, Keitaro Eizuka, Toshiaki Ando, Takafumi Nobuchi, Kohei Kawasaki, Tomoaki Saito, Manabu Iyoda, Dai Nakashima, Atsushi Kasamatsu, Hideki Tanzawa
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85242-1