Chimeric antigen receptor T-cell therapy-induced nervous system toxicity: a real-world study based on the FDA Adverse Event Reporting System database

Chimeric antigen receptor T-cell therapy-induced nervous system toxicity: a real-world study based on the FDA Adverse Event Reporting System database

Abstract Background Nervous system toxicity (NST) is one of the most frequent and dangerous side effects of chimeric antigen receptor T-cell (CAR-T) therapy, which is an effective treatment for related tumors in most relapsed/refractory (r/r) hematologic malignancies. Current clinical trial data do...

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Bibliographic Details
Main Authors: Xiayang Ren, Guanmin Zhang, Guohui Li, Yanfeng Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
CAR-T therapy
Nervous system toxicity
Pharmacovigilance
FDA Adverse Event Reporting System (FAERS)
Online Access:https://doi.org/10.1186/s12885-023-11753-x

Internet

https://doi.org/10.1186/s12885-023-11753-x

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