SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy

ABSTRACTTemozolomide (TMZ) is the primary chemotherapeutic drug for treating glioblastoma (GBM); however, the final clinical outcome is considerably limited by the poor response and resistance to TMZ. Although autophagy is thought to be associated with chemotherapy resistance and cancer cell surviva...

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Bibliographic Details
Main Authors: Jie Yu, Lin Han, Feng Yang, Mingliang Zhao, Hong Zhou, Linwang Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-06-01
Series:Bioengineered
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2022.2081463