Differential Impacts on Tensional Homeostasis of Gastric Cancer Cells Due to Distinct Domain Variants of E-Cadherin

Differential Impacts on Tensional Homeostasis of Gastric Cancer Cells Due to Distinct Domain Variants of E-Cadherin

In epithelia, breakdown of tensional homeostasis is closely associated with E-cadherin dysfunction and disruption of tissue function and integrity. In this study, we investigated the effect of E-cadherin mutations affecting distinct protein domains on tensional homeostasis of gastric cancer cells. W...

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Bibliographic Details
Main Authors: Han Xu, Katie A. Bunde, Joana Figueiredo, Raquel Seruca, Michael L. Smith, Dimitrije Stamenović
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
tensional homeostasis
traction microscopy
gastric cancer cells
E-cadherin mutations
extracellular matrix proteins
Online Access:https://www.mdpi.com/2072-6694/14/11/2690

Internet

https://www.mdpi.com/2072-6694/14/11/2690

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