Nuclear Receptor Small Heterodimer Partner in Apoptosis Signaling and Liver Cancer

Small heterodimer partner (SHP, NR0B2) is a unique orphan nuclear receptor that contains the dimerization and a putative ligand-binding domain, but lacks the conserved DNA binding domain. SHP exerts its physiological function as an inhibitor of gene transcription through physical interaction with mu...

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Bibliographic Details
Main Authors: Li Wang, Yuxia Zhang
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/1/198/