Clinical Validation of a Plasma Donor-derived Cell-free DNA Assay to Detect Allograft Rejection and Injury in Lung Transplant

Background. Lung transplant patients are vulnerable to various forms of allograft injury, whether from acute rejection (AR) (encompassing acute cellular rejection [ACR] and antibody-mediated rejection [AMR]), chronic lung allograft dysfunction (CLAD), or infection (INFXN). Previous research indicate...

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Bibliographic Details
Main Authors: Justin P. Rosenheck, DO, David J. Ross, MD, Mena Botros, MD, Alexander Wong, MD, Jonathan Sternberg, PhD, Yen-An Chen, MS, Nathan Liang, BA, Amy Baer, MS, Ebad Ahmed, PhD, Ryan Swenerton, PhD, Bernhard G. Zimmermann, PhD, Gordon Fehringer, PhD, Zachary P. Demko, PhD, Michael Olymbios, MD, Paul R. Billings, MD, PhD, Brian C. Keller, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2022-04-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001317