Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets

Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets

Background: Sepsis is a clinical syndrome, due to a dysregulated inflammatory response to infection. Accumulating evidence shows that human leukocyte antigen (HLA) genes play a key role in the immune responses to sepsis. Nevertheless, the effects of HLA genes in sepsis have still not been comprehens...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zhen Chen, Rui Chen, Yangpeng Ou, Jianhai Lu, Qianhua Jiang, Genglong Liu, Liping Wang, Yayun Liu, Zhujiang Zhou, Ben Yang, Liuer Zuo
التنسيق: مقال
اللغة:English
منشور في: Frontiers Media S.A. 2022-05-01
سلاسل:Frontiers in Physiology
الموضوعات:
sepsis
HLA genes
immune infiltration
immunosuppression
model
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fphys.2022.870657/full

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