Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets

Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets

Background: Sepsis is a clinical syndrome, due to a dysregulated inflammatory response to infection. Accumulating evidence shows that human leukocyte antigen (HLA) genes play a key role in the immune responses to sepsis. Nevertheless, the effects of HLA genes in sepsis have still not been comprehens...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhen Chen, Rui Chen, Yangpeng Ou, Jianhai Lu, Qianhua Jiang, Genglong Liu, Liping Wang, Yayun Liu, Zhujiang Zhou, Ben Yang, Liuer Zuo
Materialtyp: Artikel
Språk:English
Publicerad: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Physiology
Ämnen:
sepsis
HLA genes
immune infiltration
immunosuppression
model
Länkar:https://www.frontiersin.org/articles/10.3389/fphys.2022.870657/full

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