Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of adults with tuberculosis infection and disease

Detection of Mycobacterium tuberculosis DNA in CD34+ peripheral blood mononuclear cells of adults with tuberculosis infection and disease

Objectives: To investigate whether Mycobacterium tuberculosis (Mtb) DNA is detected in peripheral blood mononuclear cells (PBMC) of subjects with tuberculosis (TB) or TB infection (TBI) living in a low-burden country. Methods: We prospectively enrolled 57 patients with TB, 41 subjects with TBI, and...

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Bibliographic Details
Main Authors: Federica Repele, Tonino Alonzi, Assunta Navarra, Chiara Farroni, Andrea Salmi, Gilda Cuzzi, Giovanni Delogu, Gina Gualano, Vincenzo Puro, Gabriella De Carli, Enrico Girardi, Fabrizio Palmieri, Adrian R. Martineau, Delia Goletti
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:International Journal of Infectious Diseases
Subjects:
Tuberculosis infection
Mycobacterium tuberculosis
ddPCR
IGRA
Tuberculosis niche
CD34+ cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224000705

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http://www.sciencedirect.com/science/article/pii/S1201971224000705

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