Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes

Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes

Abstract Background Salivary glands produce saliva that play essential roles in digestion and oral health. Derivation of salivary gland organoids from pluripotent stem cells (PSCs) provides a powerful platform to model the organogenesis processes during development. A few studies attempted to differ...

Full description

Bibliographic Details
Main Authors: Siqi Zhang, Yi Sui, Shuang Yan, Yifei Zhang, Chong Ding, Xiaodong Su, Jingwei Xiong, Shicheng Wei
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Pluripotent stem cells
Three-dimensional cultures
Salivary glands
Organogenesis
Modeling
Online Access:https://doi.org/10.1186/s13287-022-03033-5

Internet

https://doi.org/10.1186/s13287-022-03033-5

Similar Items