The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages

The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages

Norovirus is an acute infection of the gastrointestinal tract causing rapid induction of vomiting and diarrhoea. The infection is sensed and controlled by the innate immune system, particularly by the RNA helicase MDA-5 and type I and III interferons (IFNs). We have observed that intracellular repli...

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Bibliographic Details
Main Authors: Svenja Fritzlar, Peter A. White, Jason M. Mackenzie
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Viruses
Subjects:
mouse norovirus
innate immunity
microtubules
GEF-H1
Online Access:http://www.mdpi.com/1999-4915/11/1/47

Internet

http://www.mdpi.com/1999-4915/11/1/47

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