The integrin-linked kinase-PINCH-parvin complex supports integrin αIIbβ3 activation.

Integrin-linked kinase (ILK) is an important signaling regulator that assembles into the heteroternary complex with adaptor proteins PINCH and parvin (termed the IPP complex). We recently reported that ILK is important for integrin activation in a Chinese hamster ovary (CHO) cell system. We previous...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Shigenori Honda, Hiroko Shirotani-Ikejima, Seiji Tadokoro, Yoshiaki Tomiyama, Toshiyuki Miyata
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS ONE
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24376884/?tool=EBI